Anti-E-Selectin antibody
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概述
- 产品描述The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
- 产品名称Anti-E-Selectin antibody
- 分子量65 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from mouse E-Selectin 501-612/612
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Membrane; Single-pass type I membrane protein.
- 其它名称CD 62E
CD26E
CD62 antigen-like family member E
CD62E
CD62E antigen
E selectin
E-selectin
ELAM 1
ELAM
ELAM-1
ELAM1
Endothelial adhesion molecule 1
Endothelial leukocyte adhesion molecule 1
ESEL
LECAM 2
LECAM2
Leukocyte endothelial cell adhesion molecule 2
Leukocyte-endothelial cell adhesion molecule 2
LYAM2_HUMAN
SELE
Selectin E
SelectinE.
more
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应用
WB:1:500-2000
IHC-P:1:400-800
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Fig1: Sample: HL-60 Cell (Human) Lysate at 40 ug
Primary: Anti- E-Selectinat 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
Fig2: Sample: Liver (Mouse) Lysate at 40 ug
Primary: Anti- E-Selectinat 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
Fig3: Sample:
DU145 Cell Lysate at 40 ug
LOVO Cell Lysate at 40 ug
Primary: Anti-E-Selectin (wt-p53)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 63 kD
Fig4: Sample: Siha Cell Lysate at 40 ug
Primary: Anti- E-Selectinat 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kD
Observed band size: 65 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
