Anti-PBR antibody
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概述
- 产品描述Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
- 产品名称Anti-PBR antibody
- 分子量10/18 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified
- 亚细胞定位Mitochondrion.
- 其它名称Benzodiazapine receptor (peripheral) antibody
Benzodiazepine peripheral binding site antibody
BPBS antibody
BZRP antibody
DBI antibody
IBP antibody
Isoquinoline carboxamide-binding protein antibody
MBR antibody
mDRC antibody
Mitochondrial benzodiazepine receptor antibody
PBR antibody
PBS antibody
Peripheral benzodiazepine receptor antibody
Peripheral benzodiazepine receptor-related protein antibody
Peripheral type benzodiazepine receptor antibody
Peripheral-type benzodiazepine receptor antibody
pk18 antibody
PKBS antibody
PTBR antibody
Ptbzr antibody
PTBZR02 antibody
RATPTBZR02 antibody
translocator protein (18kDa) antibody
Translocator protein antibody
Tspo antibody
Tspo1 antibody
TSPOA_HUMAN antibody
more
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应用
WB: 1:500-1:2,000
IHC-P: 1:50-1:200
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Fig1: Western blot analysis of PBR on A431 and PC-3M cell lysateS using anti-PBR antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PBR antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-PBR antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PBR antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-PBR antibody. Counter stained with hematoxylin.
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