Anti-PSMA antibody
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概述
- 产品描述Prostate cancer is the most frequently diagnosed cancer and the early detection of prostate cancer dramatically and efficiently reduces the observed mortality rate. Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Conversely, STEAP (six-transmembrane epithelial antigen of the prostate), prostate carcinoma tumor antigen (PCTA-1) and prostate-specific membrane antigen (PSM) represent additional prostate-specific antigens that are overexpressed only in malignant tumors and therefore are more specific identifiers of malignancies. PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein.
- 产品名称Anti-PSMA antibody
- 分子量50/85 kDa
- 种属反应性Human
- 验证应用WB,ICC,FC
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cytoplasm. Cell membrane.
- 其它名称Cell growth inhibiting protein 27 antibody
Cell growth-inhibiting gene 27 protein antibody
FGCP antibody
Folate hydrolase (prostate-specific membrane antigen) 1 antibody
Folate hydrolase 1 antibody
Folate hydrolase antibody
Folate hydrolase prostate specific membrane antigen 1 antibody
FOLH 1 antibody
FOLH antibody
Folh1 antibody
FOLH1_HUMAN antibody
Folylpoly gamma glutamate carboxypeptidase antibody
Folylpoly-gamma-glutamate carboxypeptidase antibody
GCP 2 antibody
GCP II antibody
GCP2 antibody
GCPII antibody
GIG27 antibody
Glutamate carboxylase II antibody
Glutamate carboxypeptidase 2 antibody
Glutamate carboxypeptidase II antibody
Membrane glutamate carboxypeptidase antibody
mGCP antibody
N acetylated alpha linked acidic dipeptidase 1 antibody
N-acetylated-alpha-linked acidic dipeptidase I antibody
NAALAD 1 antibody
NAALAD1 antibody
NAALAdase antibody
NAALADase I antibody
Prostate specific membrane antigen antibody
Prostate specific membrane antigen variant F antibody
Prostate-specific membrane antigen antibody
PSM antibody
PSMA antibody
Pteroylpoly gamma glutamate carboxypeptidase antibody
Pteroylpoly-gamma-glutamate carboxypeptidase antibody
more
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应用
WB: 1:500-1:1,000
ICC: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis of PSMA on human small intestine tissue lysate using anti-PSMA antibody at 1/1,000 dilution.
Fig2: ICC staining PSMA in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining PSMA in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Flow cytometric analysis of HepG2 cells with PSMA antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
