Anti-IL-7R-alpha antibody
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概述
- 产品描述Interleukin 7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor g chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of insulin receptor substrate-1 (IRS-1) and insulin receptor substrate-2 (IRS-2), originally called 4PS.
- 产品名称Anti-IL-7R-alpha antibody
- 分子量52 kDa
- 种属反应性Human,Zebrafish
- 验证应用WB,IHC-P,FC
- 抗体类型兔多抗
- 免疫原Recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Membrane. Secreted.
- 其它名称CD 127 antibody
CD127 antibody
CD127 antigen antibody
CDw127 antibody
IL 7R alpha antibody
IL 7R antibody
IL-7 receptor subunit alpha antibody
IL-7R subunit alpha antibody
IL-7R-alpha antibody
IL-7RA antibody
IL7R antibody
IL7RA antibody
IL7RA_HUMAN antibody
IL7Ralpha antibody
ILRA antibody
Interleukin 7 receptor alpha chain antibody
Interleukin 7 receptor antibody
Interleukin 7 receptor isoform H5 6 antibody
Interleukin-7 receptor subunit alpha antibody
more
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应用
WB: 1:500-1:1,000
IHC-P: 1:50-1:200
FC: 1:50-1:100
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Fig1: Western blot analysis of IL-7R-alpha on zebrafish tissue lysate using anti-IL-7R-alpha antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded zebrafish tissue using anti-IL-7R-alpha antibody. Counter stained with hematoxylin.
Fig3: Flow cytometric analysis of Daudi cells with IL-7R-alpha antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
