Anti-NM23 antibody
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概述
- 产品描述Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
- 产品名称Anti-NM23 antibody
- 分子量17/19 kDa
- 种属反应性Human,Mouse
- 验证应用ICC,IHC-P,FC,WB
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Cytoplasm. Nucleus.
- 其它名称AWD antibody
AWD, drosophila, homolog of antibody
GAAD antibody
Granzyme A activated DNase antibody
Granzyme A-activated DNase antibody
GZMA activated DNase antibody
Metastasis inhibition factor NM23 antibody
NB antibody
NBS antibody
NDK A antibody
NDKA antibody
NDKA_HUMAN antibody
NDP kinase A antibody
NDPK-A antibody
NDPKA antibody
NM23 antibody
NM23 long variant, included antibody
nm23-H1 antibody
NM23-M1 antibody
NM23H1B, included antibody
NME/NM23 nucleoside diphosphate kinase 1 antibody
Nme1 antibody
NME1-NME2 spliced read-through transcript, included antibody
Non-metastatic cells 1, protein (NM23A) expressed in antibody
Nonmetastatic cells 1, protein expressed in antibody
Nonmetastatic protein 23 antibody
Nonmetastatic protein 23, homolog 1 antibody
Nucleoside diphosphate kinase A antibody
Tumor metastatic process-associated protein antibody
more
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应用
ICC: 1:50-1:200
IHC-P: 1:50-1:200
FC: 1:50-1:100
WB: 1:500
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Fig1: ICC staining NM23 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining NM23 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining NM23 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-NM23 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-NM23 antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-NM23 antibody. Counter stained with hematoxylin.
Fig7: Flow cytometric analysis of Jurkat cells with NM23 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondar
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