Anti-TGF beta Receptor I antibody
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概述
- 产品描述On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
- 产品名称Anti-TGF beta Receptor I antibody
- 分子量55 KDa
- 种属反应性Human,Mouse,Rat,Cow
- 验证应用WB,IHC-P,ICC/IF
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human TGF-beta R1 301-400/501
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction.
- 其它名称TGFBR1
TGF Beta R1
TGF beta Receptor I
AAT 5
AAT5
Activin A receptor type II like kinase 53kDa
Activin receptor like kinase 5
ACVRLK 4
ACVRLK4
ALK 5
ALK5
Serine/threonine protein kinase receptor R4
SKR 4
SKR4
TbetaR I
TGF beta receptor type 1
TGF beta receptor type I
TGF beta type I receptor
TGFBR 1
TGFBR1 protein
TGFR 1
TGFR1
Transforming growth factor beta receptor I
more
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应用
WB:1:500-2000
IHC-P:1:400-800
IF:1:100-500
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Fig1: Sample:
Lane 1: Gastric carcinoma(Human) Lysate at 30 ug
Lane 2:Stomach (Mouse) Lysate at 30 ug
Primary: Anti-TGF Beta R1/TGFBR1 at 1:200 dilution;
Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000 dilution;
Predicted band size : 55kD
Observed band size : 55kD
Fig2: Sample: Small intestine (Mouse) Lysate at 30 ug
Primary: Anti- TGF beta Receptor 1 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
Fig3: Sample:
293T(Human) Cell Lysate at 40 ug
A431(Human) Cell Lysate at 40 ug
Primary: Anti-TGF beta Receptor I (bs-10196R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
