Anti-TBX1 antibody
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概述
- 产品描述T-box transcription factor TBX1 also known as T-box protein 1 and testis-specific T-box protein is a protein that in humans is encoded by the TBX1 gene. Genes in the T-box family are transcription factors that play important roles in the formation of tissues and organs during embryonic development. To carry out these roles, proteins made by this gene family bind to specific areas of DNA called T-box binding element (TBE) to control the expression of target genes. The T-box 1 protein appears to be necessary for the normal development of large arteries that carry blood out of the heart, muscles and bones of the face and neck, and glands such as the thymus and parathyroid. Although the T-box 1 protein acts as a transcription factor, it is not yet known which genes are regulated by the protein. Most cases of 22q11.2 deletion syndrome are caused by the deletion of a small piece of chromosome 22. This region of the chromosome contains about 30 genes, including the TBX1 gene. In a small number of affected individuals without a chromosome 22 deletion, mutations in the TBX1 gene are thought to be responsible for the characteristic signs and symptoms of the syndrome. Of the three known mutations, two mutations change one amino acid (a building block of proteins) in the T-box 1 protein. The third mutation deletes a single amino acid from the protein.
- 产品名称Anti-TBX1 antibody
- 分子量43 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human TBX1 165-270/398
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Affinity purified by Protein A
- 亚细胞定位Nucleus.
- 其它名称CAFS
CTHM
DGCR
DGS
DORV
T box 1
T box 1 transcription factor
T box 1 transcription factor C
T box
T box protein 1
T box transcription factor TBX 1
T box transcription factor TBX1
T-box 1
T-box protein 1
T-box transcription factor TBX1
TBX 1
TBX 1C
tbx1
TBX1_HUMAN
TBX1C
Testis specific T box protein
Testis-specific T-box protein
TGA
VCFS.
more
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Fig1: Sample: Brain (Rat) Lysate at 40 ug
Primary: Anti-TBX1 at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 43 kD
Observed band size: 44 kD
Fig2: Sample: Muscle (Mouse) Lysate at 40 ug
Primary: Anti-TBX1at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 43 kD
Observed band size: 43 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
